Thymidine triphosphate
From Wikipedia the free encyclopedia
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| Names | |
|---|---|
| IUPAC name Thymidine 5′-(tetrahydrogen triphosphate) | |
| Systematic IUPAC name O1-{[(2R,3S,5R)-5-(2,4-Dioxo-5-methyl-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate | |
| Other names dTTP, 2′-Deoxythymidine triphosphate | |
| Identifiers | |
3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
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| ECHA InfoCard | 100.006.064 |
| MeSH | thymidine+5'-triphosphate |
PubChem CID | |
| UNII | |
CompTox Dashboard (EPA) | |
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| Properties | |
| C10H17N2O14P3 | |
| Molar mass | 482.168 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Thymidine triphosphate (TTP), also called deoxythymidine triphosphate (dTTP),[1] is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA. Unlike the other deoxyribonucleoside triphosphates, thymidine triphosphate does not always contain the "deoxy" prefix in its name.[2] The corresponding ribonucleoside triphosphate is called uridine triphosphate.
It can be used by DNA ligase to create overlapping "sticky ends" so that protruding ends of opened microbial plasmids may be closed up.
References[edit]
- ^ "Thymidine 5'-triphosphate (PAMDB000346)". University of Maryland, Baltimore. 2018-01-22. Archived from the original on 2023-10-29. Retrieved 2023-10-29.
- ^ Coghill, Anne M.; Garson, Lorrin R., eds. (2006). The ACS style guide: effective communication of scientific information (3rd ed.). Washington, D.C.: American Chemical Society. p. 244. ISBN 978-0-8412-3999-9.
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