Androgen receptor degrader
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Type of drug
Not to be confused with Selective androgen receptor modulator.
A (selective) androgen receptor degrader or downregulator (SARD) is a type of drug which interacts with the androgen receptor (AR) such that it causes the AR to be degraded and thus downregulated.[1] They are under investigation for the treatment of prostate cancer and other androgen-dependent conditions.[1]
As of 2017, dimethylcurcumin (ASC-J9), a SARD, is under development for the treatment of acne vulgaris.[2]
See also[edit]
References[edit]
ARTooltip Androgen receptor |
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GPRC6A |
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