OR3A3

OR3A3
Identifiers
Aliases	OR3A3, OR17-137, OR17-16, OR17-201, OR3A6, OR3A7, OR3A8P, olfactory receptor family 3 subfamily A member 3
External IDs	MGI: 3030245 HomoloGene: 74999 GeneCards: OR3A3
Gene location (Human)
Chr.	Chromosome 17 (human)
End	3,424,070 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	74,243,476 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; mesencephalon; ; lymph node; ; substantia nigra; ; placenta; ; myometrium; ; thigh; ; putamen; ; hippocampal formation; ; hippocampus proper;
	Top expressed in
	colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	8392
	258704
	ENSG00000159961
	ENSMUSG00000054406
	P47888
	n/a
	NM_012373; NM_001386098
	NM_146709
	NP_036505
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Olfactory receptor 3A3 is a protein that in humans is encoded by the OR3A3 gene.^[5]^[6]^[7]

Function[edit]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[7]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000159961 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000054406 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet. 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088.
^ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.
^ ^a ^b "Entrez Gene: OR3A3 olfactory receptor, family 3, subfamily A, member 3".

External links[edit]

OR3A3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000159961 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000054406 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8004088-5] Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet. 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088.

[pmid9500546-6] Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.

[entrez-7] "Entrez Gene: OR3A3 olfactory receptor, family 3, subfamily A, member 3".

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OR3A3

Function[edit]

See also[edit]

References[edit]

Further reading[edit]

External links[edit]

OR3A3

Function[edit]

See also[edit]

References[edit]

Further reading[edit]

External links[edit]

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