Cloxestradiol

Cloxestradiol
Clinical data
Other names17-(2,2,2-Trichloroethoxy)estradiol; 17-(1-Hydroxy-2,2,2-trichloroethoxy)estra-1,3,5(10-trien-3-ol
Drug classEstrogen; Estrogen ether
Identifiers
  • (8R,9S,13S,14S,17S)-13-methyl-17-(2,2,2-trichloro-1-hydroxyethoxy)-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-ol
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H25Cl3O3
Molar mass419.77 g·mol−1
3D model (JSmol)
  • C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CC[C@@H]2OC(C(Cl)(Cl)Cl)O)O
  • InChI=1S/C20H25Cl3O3/c1-19-9-8-14-13-5-3-12(24)10-11(13)2-4-15(14)16(19)6-7-17(19)26-18(25)20(21,22)23/h3,5,10,14-18,24-25H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18?,19+/m1/s1
  • Key:JVLHMVXGPLKLFV-AJUWMHLFSA-N

Cloxestradiol (INNTooltip International Nonproprietary Name), also known as 17-(2,2,2-trichloroethoxy)estradiol, is a synthetic, steroidal estrogen which was never marketed.[1] It is an analogue of estradiol with a 2,2,2-trichloroethoxy substitution.[1] The O,O-diacetate derivative, cloxestradiol acetate (brand name Genovul), has been marketed as an estrogen.[1]

See also

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References

[edit]
  1. ^ a b c Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 308–. ISBN 978-1-4757-2085-3.



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