Tolpropamine

Tolpropamine
Clinical data
ATC code	D04AA12 (WHO) ;
Identifiers
	IUPAC name N,N-dimethyl-3-(4-methylphenyl)-3-phenylpropan-1-amine;
CAS Number	5632-44-0 3354-67-4;
PubChem CID	72141;
ChemSpider	65115 ;
UNII	TBZ8909KFS;
KEGG	D07196 ;
CompTox Dashboard (EPA)	DTXSID30863584 ;
ECHA InfoCard	100.024.611
Chemical and physical data
Formula	C18H23N
Molar mass	253.389 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES c1cc(ccc1C(c2ccccc2)CCN(C)C)C;
	InChI InChI=1S/C18H23N/c1-15-9-11-17(12-10-15)18(13-14-19(2)3)16-7-5-4-6-8-16/h4-12,18H,13-14H2,1-3H3 ; Key:CINROOONPHQHPO-UHFFFAOYSA-N ;
	(verify)

Tolpropamine is an antihistamine and anticholinergic used as an antipruritic.^[1]

References

^ Kutscher B (2000-06-15). "Dermatologicals (D), 2. Antifungals (D01), Emollients and Protectives (D02), and Antipruritics (D04) for Dermatological Use". In Ley C (ed.). Ullmann's Encyclopedia of Industrial Chemistry. pp. 1–24. doi:10.1002/14356007.w08_w01. ISBN 978-3-527-30385-4. S2CID 225510885.

This dermatologic drug article is a stub. You can help Wikipedia by expanding it.

v t e Antipruritics (D04)
Antihistamines for topical use	Bamipine Chloropyramine Chlorphenoxamine Clemastine Dimetindene Diphenhydramine Isothipendyl Mepyramine Pheniramine Promethazine Thenalidine Thonzylamine Tolpropamine Tripelennamine
Anesthetics for topical use	Benzocaine Cinchocaine Dibucaine Lidocaine Oxybuprocaine Pramocaine Quinisocaine Tetracaine
Others	Corticosteroids (e.g., hydrocortisone) Counterirritants (e.g., mint oil, menthol, camphor) Difelikefalin Doxepin Nalfurafine

Clinical data

ATC code	D04AA12 (WHO)
Identifiers
IUPAC name N,N-dimethyl-3-(4-methylphenyl)-3-phenylpropan-1-amine
CAS Number	5632-44-0 3354-67-4
PubChem CID	72141
ChemSpider	65115^Y
UNII	TBZ8909KFS
KEGG	D07196^Y
CompTox Dashboard (EPA)	DTXSID30863584
ECHA InfoCard	100.024.611
Chemical and physical data
Formula	C₁₈H₂₃N
Molar mass	253.389 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES c1cc(ccc1C(c2ccccc2)CCN(C)C)C
InChI InChI=1S/C18H23N/c1-15-9-11-17(12-10-15)18(13-14-19(2)3)16-7-5-4-6-8-16/h4-12,18H,13-14H2,1-3H3^Y Key:CINROOONPHQHPO-UHFFFAOYSA-N^Y
(verify)