Hepatitis C virus nonstructural protein 4B

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HCV genome

Nonstructural protein 4B (NS4B) is a viral protein found in the hepatitis C virus.[1] It has mass of 27 kDa and probably involved in process of intracellular membrane structure formation to allow virus replication.[2]


  1. ^ Beld M, Penning M, van Putten M, et al. (October 1998). "Hepatitis C virus serotype-specific core and NS4 antibodies in injecting drug users participating in the Amsterdam cohort studies". J. Clin. Microbiol. 36 (10): 3002–6. doi:10.1128/JCM.36.10.3002-3006.1998. PMC 105101. PMID 9738057.
  2. ^ Ella H Sklan and Jeffrey S Glenn. Chapter 8. HCV NS4B: From Obscurity to Central Stage in "Hepatitis C Viruses: Genomes and Molecular Biology." / Tan SL. — Norfolk: Horizon Bioscience, 2006.