BBX (gene)

BBX
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WZ6
Identifiers
Aliases	BBX, ARTC1, HBP2, HSPC339, MDS001, bobby sox homolog (Drosophila), HMG-box containing
External IDs	MGI: 1917758; HomoloGene: 10634; GeneCards: BBX; OMA:BBX - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	107,811,324 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	50,252,753 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; tail of epididymis; ; caput epididymis; ; corpus callosum; ; lactiferous duct; ; inferior ganglion of vagus nerve; ; seminal vesicula; ; Achilles tendon; ; saphenous vein; ; testicle;
	Top expressed in
	cumulus cell; ; spermatid; ; ascending aorta; ; pineal gland; ; pituitary gland; ; seminiferous tubule; ; aortic valve; ; lumbar spinal ganglion; ; stroma of bone marrow; ; tail of embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; cytosol;
Biological process	bone development; regulation of transcription, DNA-templated; transcription, DNA-templated; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	56987
	70508
	ENSG00000114439
	ENSMUSG00000022641
	Q8WY36
	Q8VBW5
	NM_001142568; NM_001276286; NM_020235
	NM_027444; NM_001347240
	NP_001136040; NP_001263215; NP_064620
	NP_001334169; NP_081720
	Wikidata
View/Edit Human	View/Edit Mouse

HMG box transcription factor BBX also known as bobby sox homolog or HMG box-containing protein 2 is a protein that in humans is encoded by the BBX gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000114439 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022641 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: bobby sox homolog (Drosophila)". Retrieved 2011-08-30.

External links

Human BBX genome location and BBX gene details page in the UCSC Genome Browser.

Caporaso N, Gu F, Chatterjee N, Sheng-Chih J, Yu K, Yeager M, Chen C, Jacobs K, Wheeler W, Landi MT, Ziegler RG, Hunter DJ, Chanock S, Hankinson S, Kraft P, Bergen AW (2009). "Genome-wide and candidate gene association study of cigarette smoking behaviors". PLOS ONE. 4 (2): e4653. Bibcode:2009PLoSO...4.4653C. doi:10.1371/journal.pone.0004653. PMC 2644817. PMID 19247474.
Wang HY, Peng G, Guo Z, Shevach EM, Wang RF (Mar 2005). "Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells". Journal of Immunology. 174 (5): 2661–70. doi:10.4049/jimmunol.174.5.2661. PMID 15728473.
Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C (Aug 2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling". Gut. 58 (8): 1078–83. doi:10.1136/gut.2008.169052. PMID 19240061. S2CID 17111427.
Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Sánchez-Díaz A, Blanco MA, Jones N, Moreno S (Sep 2001). "HBP2: a new mammalian protein that complements the fission yeast MBF transcription complex". Current Genetics. 40 (2): 110–8. doi:10.1007/s002940100241. PMID 11680820. S2CID 30444254.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000114439 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022641 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: bobby sox homolog (Drosophila)". Retrieved 2011-08-30.

[1]

[2]

[3]

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[5]

BBX (gene)

References

External links

Further reading

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