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Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Kitrinoviricota
Class: Alsuviricetes
Order: Hepelivirales
Family: Alphatetraviridae

Alphatetraviridae is a family of viruses. Moths and butterflies serve as natural hosts. There are two genera in the family. Infection outcome varies from unapparent to lethal.[1][2]


The following genera are assigned to the family:[2]


Viruses in Alphatetraviridae are non-enveloped, with icosahedral geometries, and T=4 symmetry. The diameter is around 40 nm. Genomes are linear and non-segmented, bipartite, around 6.5kb in length.[1]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Betatetravirus Icosahedral T=4 Non-enveloped Linear Monopartite
Omegatetravirus Icosahedral T=4 Non-enveloped Linear Segmented

Life cycle[edit]

Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded rna virus transcription is the method of transcription. Translation takes place by leaky scanning, and ribosomal skipping. Moths and butterflies serve as the natural host. Transmission routes are oral.[1]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Betatetravirus Moths; butterflies Midgut Cell receptor endocytosis Budding Cytoplasm Cytoplasm Oral
Omegatetravirus Moths; butterflies Midgut Cell receptor endocytosis Budding Cytoplasm Cytoplasm Oral


  1. ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 14 May 2021.

External links[edit]