CPSF2
CPSF2 (Cleavage and polyadenylation specific factor 2) هوَ بروتين يُشَفر بواسطة جين CPSF2 في الإنسان.[1][2][3]
الوظيفة
[عدل]هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
[عدل]هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
[عدل]- ^ Samiotaki M، Balatsos NA، Courtis N، Tsiapalis CM (يناير 2001). "Assignment of the 100-kDa subunit of cleavage and polyadenylation specificity factor (CPSF2) to human chromosome 14q31.3 by radiation hybrid mapping". Cytogenet Cell Genet. ج. 90 ع. 3–4: 328–9. DOI:10.1159/000056798. PMID:11124543.
- ^ Jenny A، Hauri HP، Keller W (ديسمبر 1994). "Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit". Mol Cell Biol. ج. 14 ع. 12: 8183–90. PMC:359357. PMID:7969155.
- ^ "Entrez Gene: CPSF2 cleavage and polyadenylation specific factor 2, 100kDa". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
[عدل]- Murthy KG، Manley JL (1995). "The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation". Genes Dev. ج. 9 ع. 21: 2672–83. DOI:10.1101/gad.9.21.2672. PMID:7590244.
- Thuresson AC، Aström J، Aström A، وآخرون (1994). "Multiple forms of poly(A) polymerases in human cells". Proc. Natl. Acad. Sci. U.S.A. ج. 91 ع. 3: 979–83. DOI:10.1073/pnas.91.3.979. PMC:521437. PMID:8302877.
- Bienroth S، Keller W، Wahle E (1993). "Assembly of a processive messenger RNA polyadenylation complex". EMBO J. ج. 12 ع. 2: 585–94. PMC:413241. PMID:8440247.
- Schul W، Groenhout B، Koberna K، وآخرون (1996). "The RNA 3' cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA". EMBO J. ج. 15 ع. 11: 2883–92. PMC:450226. PMID:8654386.
- McCracken S، Fong N، Yankulov K، وآخرون (1997). "The C-terminal domain of RNA polymerase II couples mRNA processing to transcription". Nature. ج. 385 ع. 6614: 357–61. DOI:10.1038/385357a0. PMID:9002523.
- Takagaki Y، Manley JL (2000). "Complex protein interactions within the human polyadenylation machinery identify a novel component". Mol. Cell. Biol. ج. 20 ع. 5: 1515–25. DOI:10.1128/MCB.20.5.1515-1525.2000. PMC:85326. PMID:10669729.
- Nagase T، Kikuno R، Ishikawa KI، وآخرون (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. ج. 7 ع. 1: 65–73. DOI:10.1093/dnares/7.1.65. PMID:10718198.
- Monsalve M، Wu Z، Adelmant G، وآخرون (2000). "Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1". Mol. Cell. ج. 6 ع. 2: 307–16. DOI:10.1016/S1097-2765(00)00031-9. PMID:10983978.
- de Vries H، Rüegsegger U، Hübner W، وآخرون (2000). "Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors". EMBO J. ج. 19 ع. 21: 5895–904. DOI:10.1093/emboj/19.21.5895. PMC:305781. PMID:11060040.
- Hodgman R، Tay J، Mendez R، Richter JD (2001). "CPEB phosphorylation and cytoplasmic polyadenylation are catalyzed by the kinase IAK1/Eg2 in maturing mouse oocytes". Development. ج. 128 ع. 14: 2815–22. PMID:11526086.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Kaufmann I، Martin G، Friedlein A، وآخرون (2005). "Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase". EMBO J. ج. 23 ع. 3: 616–26. DOI:10.1038/sj.emboj.7600070. PMC:1271804. PMID:14749727.
- Beausoleil SA، Jedrychowski M، Schwartz D، وآخرون (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. ج. 101 ع. 33: 12130–5. DOI:10.1073/pnas.0404720101. PMC:514446. PMID:15302935.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Kimura K، Wakamatsu A، Suzuki Y، وآخرون (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. ج. 16 ع. 1: 55–65. DOI:10.1101/gr.4039406. PMC:1356129. PMID:16344560.
- Olsen JV، Blagoev B، Gnad F، وآخرون (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. ج. 127 ع. 3: 635–48. DOI:10.1016/j.cell.2006.09.026. PMID:17081983.
- Ewing RM، Chu P، Elisma F، وآخرون (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. ج. 3 ع. 1: 89. DOI:10.1038/msb4100134. PMC:1847948. PMID:17353931.